INFLUENCE OF FATS OF VARIOUS ORIGINS ON THE REPRODUCTIVE FUNCTION OF EXPERIMENTAL ANIMALS
DOI:
https://doi.org/10.32782/2450-8640.2024.1.2Keywords:
spermatogenesis, male rats, palm oil, refined sunflower oil, margarineAbstract
In Ukraine, about 50–60 thousand men annually turn to specialists with sexual and andrological problems for help. Today, about 80% of men admit that having problems in the sexual sphere seriously affects the quality of life. At the same time, the leading place is occupied by the issue of the safe impact of chronic consumption of dietary fats on reproductive function. The aim of the study was to study the effect of long-term consumption of dietary fats of various origins on the spermatogenic function of the testes of male rats. The studies were carried out on 7 month old male rats of the Wistar population after 75 days of consumption of fats of various origins (palm oil, refined sunflower oil, margarine) at a rate of 3 mg/kg. At the end of the experiment, the state of spermatogenesis in a suspension of epididymal spermatozoa was assessed in males. In experimental animals, it was observed: a decrease in the total concentration of gametes, a deficiency of morphologically normal cells and the emergence of a significant number of abnormal forms of spermatozoa. Relative to control males, a decrease in the total concentration of gametes was found in the Palm oil group by 22%, in the Margarine group – by 30.2%, in the Refined sunflower oil group – by 34%. A decrease in the total number of gametes led to a deficit of morphologically normal forms in all experimental animals. In the “Palm oil” group the shortage was 25%, in the “Margarine” group – 24%, in the “Refined sunflower oil” group – 36% relative to the control animals. When determining the percentage of mobile gametes, there was found deficiency only in the “Margarine” group. It was 20% relative to the indicators of control males. But the percentage of abnormal forms of gametes in the group “Margarine” remained at the level of indicators of the control males. And in the groups “Palm oil” and “Refined sunflower oil” an excess of this was found indicator by 67% and 61%, respectively. The experimental data obtained indicate that the consumption of dietary fats leads to disruption of all the constituent stages of spermatogenesis in adult male rats.
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