THE INFLUENCE OF NANOZINC ON THE MORPHOLOGICAL INDICATORS OF THE BLOOD OF RABBITS

Abstract

The functioning of the mammalian body is influenced by a number of factors, but the most important is balanced nutrition in terms of all nutritional components, especially bioavailable minerals. In the scientific literature, there is a lot of information about conducting research using nanominerals, and their ambiguous impact on the body of mammals is shown. Therefore, the aim of our research was to find out the effect of drinking different doses of zinc citrate on the morphological indicators of the blood of rabbits after weaning. Research was conducted in a vivarium on rabbits of the Termon breed. The influence of different amounts of the nanocompound zinc – zinc citrate, a compound of nanotechnological origin (1,3 g/dm3, pH – 1,30, nanoparticle size – 20–60 nm), manufactured by LLC “Nanomaterials and Nanotechnologies” in Kyiv, was studied. Rabbits of the control group consumed granulated compound feed, balanced according to established nutritional parameters. Rabbits of experimental groups D-I; D-II and D-III, in addition to the basic ration, additionally with water during the day received the zinc citrate compound in the amount of 0,30, respectively; 0,60 and 0,90 mg Zn/kg body weight. On the 5’th day of the preparatory period and on the 14’th, 28’th and 42’nd days, blood tests were performed. It was established that the use of zinc citrate at the rate of 0,30 mg Zn/kg of body weight was affected by minor changes in blood cells with a probable increase in the number of platelets (P < 0,05) on the 14’th day of the study. Drinking zinc citrate in the amount of 0,60 mg Zn/kg of body weight was marked by greater changes with an increase in the concentration of hemoglobin (P < 0,05), the number of monocytes (P < 0,01) on the 14’th day, the number of leukocytes (P < 0,05) on the 14’th and 28’th days and erythrocytes (P < 0,05) on the 42’nd day of the study. Zinc citrate at a dose of 0,90 mg Zn/kg of body weight was marked by the greatest changes in blood with a higher level of erythrocytes (P < 0,05), hemoglobin (P < 0,05) at 28 and 42, hematocrit (P < 0,05–0,01) on days 14 and 28, the average hemoglobin content in erythrocytes (P < 0,05) on 28, the average concentration of hemoglobin in erythrocytes (P < 0,05) during the study and the decrease in lymphocytes on day 42 of the study compared to the control.